Biostimulatory fillers offer a powerful way to rejuvenate your appearance by tapping into your body’s natural ability to produce collagen. Unlike traditional fillers that provide immediate volume, these advanced injectables work over time to rebuild structure and restore youthful firmness from within.
The expert injectors at Spa Renaissance are proud to be top providers of biostimulatory fillers in the Detroit metropolitan area. Our team has helped countless patients refresh their look with Sculptra® and Radiesse®, two of the most trusted biostimulatory injectables available.

What Are Biostimulatory Fillers?
Biostimulatory fillers, also called regenerative fillers, are collagen-stimulating injectables designed to enhance facial volume and skin texture by boosting the body’s natural collagen production. Rather than simply “filling” areas, these treatments work beneath the surface to support long-term skin renewal. They’re a smart choice for patients looking for subtle, sustained facial rejuvenation with minimal maintenance.
At Spa Renaissance, our skilled injectors specialize in both biostimulatory and traditional hyaluronic acid (HA) fillers. Your provider will help you decide which type of filler is right for your unique goals.
What Can Biostimulatory Fillers Treat?
Biostimulatory dermal fillers are especially effective in areas where collagen loss has led to sagging, hollowness, or diminished contour. These treatments are often recommended for:
- Midface volume loss – Rebuild structure in the cheeks and temples.
- Jawline sculpting – Define and refresh the lower face.
- Smile lines and marionette lines – Smooth deep facial creases.
- Chin enhancement – Improve projection and facial balance.
- Skin texture – Support collagen remodeling for firmer, smoother skin over time.
- Hand rejuvenation – Restore volume and youthfulness to aging hands.
Our Collagen-Stimulating Injectable Options
Sculptra® Injections
Sculptra® is a poly-L-lactic acid (PLLA) injectable that gradually encourages collagen synthesis. It can be ideal for patients who want subtle, progressive facial restoration without the look of “overnight” volume. Common areas treated include the cheeks, temples, jawline, and nasolabial folds.
- Collagen regeneration develops over several weeks
- Results can last up to two years or more
- Particularly effective for deeper facial hollows and structural enhancement
Radiesse® Filler Treatment
Radiesse® is made from calcium hydroxylapatite (CaHA) microspheres suspended in a gel. It offers immediate volume with the added benefit of long-term collagen stimulation.
- Delivers instant contouring results
- Stimulates collagen for extended improvement over time
- Often used for jawline, cheek, and hand rejuvenation
Benefits of Biostimulatory Fillers
- Increases collagen production for long-term skin regeneration
- Improves both volume and skin quality over time
- Minimally invasive
- Little-to-no downtime
- Longer-lasting results than traditional HA fillers
What to Expect During a Biostimulatory Filler Treatment
At Spa Renaissance, all Sculptra® and Radiesse® injections are performed with precision by experienced professionals. While many patients easily tolerate biostimulatory injections, a topical numbing cream is available to ensure your comfort if you prefer. Sessions typically take 30 to 60 minutes.
What to Expect After Collagen-Stimulating Filler Injections
Mild swelling, bruising, or tenderness may occur at the injection sites. These symptoms usually dissipate quickly. Visible improvements will develop gradually as your body produces new collagen. You can expect to see your full results over the following months, with continued benefits lasting up to two years or more.
How Much Do Biostimulatory Fillers Cost?
The cost of biostimulatory fillers in the Detroit area depends on the type of product used, amount of product needed, and number of treatments required. During your consultation, we’ll create a customized plan and provide complete pricing details.
Biostimulatory Filler FAQs
Are biostimulatory fillers safe?
Yes. Both Sculptra® and Radiesse® are FDA-approved and have been used safely for years. At Spa Renaissance, collagen-stimulating injections are performed by trained injectors who prioritize safety at every step of the treatment process.
How many sessions will I need?
The collagen-building process for biostimulatory fillers is gradual. For this reason, you may need a series of sessions spaced weeks apart, depending on the product and your treatment plan.
Sculptra® often requires multiple sessions spaced over a few months. Radiesse® may require fewer sessions. Your provider will design a treatment schedule based on your individual goals.
How long do the results last?
Sculptra® and Radiesse® can both provide results that last up to two years or more, thanks to their collagen-stimulating effects. With periodic maintenance treatments, you can extend the longevity of your results.
Can I combine biostimulatory fillers with other treatments?
Yes. Many patients can benefit from combining biostimulators with other injectables, such as HA fillers and neuromodulators like Botox®, facials, IPL photorejuvenation, or other med spa treatments for comprehensive enhancement. We’ll recommend the best combination for you based on your needs.
Why Choose Spa Renaissance?
- Extensive experience with advanced injectable techniques
- Custom treatments that align with your facial structure and goals
- Emphasis on natural-looking outcomes
- A full-service medical spa offering complete aesthetic care under one roof
Schedule Your Biostimulatory Filler Consultation Today
Ready to restore your skin from the inside out? Contact Spa Renaissance today to learn more about collagen-stimulating fillers like Sculptra® and Radiesse®. The Spa Renaissance team is proud to serve patients throughout the Detroit metropolitan area.


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Enhancing your Beauty and Confidence
The medical professionals and staff at Renaissance Plastic Surgery aim to provide a healthy approach to aging. Our goal is to prevent and reverse the effects of aging and environmental factors to make you “ Fabulous at Any Age”!
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Patient Testimonials
This was the best decision I have ever made. I met with Dr. Stefani and hired him & received a full mommy makeover. I had met with several doctors as well, as this was a big decision to make. Dr. Stefani made me feel the most comfortable and he has a great bedside manner. Also, to be completely honest after surgery …He exceeded my expectations. I almost cried after I saw what I looked like after surgery. I had 3 c sections prior and nothing was ever the same after that. I feel better than I did before kids and I wish I did this sooner. If you are even slightly hesitant …don’t be! Dr. Stefani is AMAZING.
Dr. Williams is one of the most caring and talented doctors I have ever met! I was diagnosed with breast CA 2 years ago and was referred to him for reconstruction after choosing to do a bilateral mastectomy. Boy was I scared !! He put me at ease right away with great information on what to expect along and seemed to generally care about me even though we had just met! I knew I was in the best hands! Now after 2 years, not to sound weird, I get compliments on my "new" breasts all the time, even my family Dr gave them a big WOW! Cherry on top, he did a Tummy tuck on me to even out new look, and also get compliments all the time!
Dr. Miguel is the absolute best!! I've had rhinoplasty in the past with another surgeon, and I came in for a consultation with Dr. Miguel for an alar base reduction (narrowing of nostrils). He was so honest with his answer, and he told me it was not needed. He said the procedure was unnecessary, and to leave my nose just the way it is. He told me all the things that could go wrong if I were to go forward with this procedure. I am so grateful for his honesty, and I appreciate his conservative approach. If you are looking for a rhinoplasty surgeon and want honest feedback with natural results, please consult with Dr. Miguel.